THE RELATIONSHIP OF LIFETIME SUBSTANCE-USE DISORDER WITH FAMILY FUNCTIONING, CHILDHOOD VICTIMISATION, AND DEPRESSION, AMONG JUVENILE OFFENDERS IN MALAYSIA

The relationship of lifetime substance-use disorder with family functioning, childhood victimisation, and depression, among juvenile offenders in Malaysia

Introduction: Adolescent substance use is a multifactorial social issue that leads to detrimental outcomes.The aim of this study is to understand the association of a lifetime history of substance abuse or dependence with family functioning, childhood victimisation, and depression, among adolescent male inmates in a juvenile detention centre in Mal

read more

A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients

Dravet Syndrome is an intractable form of childhood epilepsy associated with deleterious mutations in SCN1A, the gene encoding neuronal sodium channel DMSO+ALOE VERA Nav1.1.Earlier studies using human induced pluripotent stem cells (iPSCs) have produced mixed results regarding the importance of Nav1.1 in human inhibitory versus excitatory neurons.W

read more